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. Author manuscript; available in PMC: 2019 Jul 25.
Published in final edited form as: Cell Rep. 2018 Dec 11;25(11):3148–3157.e3. doi: 10.1016/j.celrep.2018.11.053

Figure 2. Striatal Dopamine Inputs Drive ChI Burst Firing through mGluRs.

Figure 2.

(A) Representative traces from ChIs showing optogenetically evoked burst response in control, presence of picrotoxin (100 μM) + CGP55845 (300 nM), DNQX (10 μM) + AP5 (10 μM), or SCH23390 (1 μM).

(B) Summary of pharmacological data.

(C) Group 1 mGluR antagonists MPEP (100 μM) and CPCCOEt (100 μM) block dopamine neuron-induced ChI burst firing.

Error bars represent SEM. *p < 0.05, **p < 0.01.