Table 1.
Protocol A | Day 0 | Day 7 | Day 14 | Day 21 | ||||||
IL-2 | x | x | x | Freeze | ||||||
Anti-CD3 | x | x | x | |||||||
Donor PBMCs | - | x | x | |||||||
Artificial APCs | x | - | - | |||||||
Rapamycin | x | - | - | |||||||
Protocol B | Day 0 | Day 7 | Day 14 | Day 21 | Day 28 | Day 35 | Day 42 | Day 49 | Day 56 | |
IL-2 | x | x | x | x | x | x | x | x | Freeze | |
Anti-CD3 | x | x | x | x | x | x | x | x | ||
Donor PBMCs | - | x | x | - | - | - | - | - | ||
Artificial APCs | x | - | - | x | x | x | x | x | ||
Rapamycin | x | - | - | - | - | - | - | - | ||
Protocol C | Day 0 | Day 7 | Day 14 | Day 21 | Day 26 | |||||
IL-2 | x | x | x | x | Freeze | |||||
Anti-CD3 | x | x | x | x | ||||||
Donor PBMCs | - | - | - | - | ||||||
Artificial APCs | x | x | x | x | ||||||
Rapamycin | x | - | - | x | ||||||
Protocol D | Day 0 | Day 7 | Day 14 | Day 21 | Day 26 | |||||
IL-2 | x | x | x | x | Freeze | |||||
Anti-CD3 | x | x | x | x | ||||||
Donor PBMCs | - | x | x | x | ||||||
Artificial APCs | x | x | x | x | ||||||
Rapamycin | x | - | - | x |