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. Author manuscript; available in PMC: 2019 Jul 26.
Published in final edited form as: Mol Psychiatry. 2019 Jan 25:10.1038/s41380-019-0359-7. doi: 10.1038/s41380-019-0359-7

Figure 5. Intracellular compartment-specific protein expression of proteasome subunits.

Figure 5.

(A). Protein expression of proteasome subunits was measured in both the nucleus- and cytosol-enriched fractions using western immunoblotting. (B) In the cytosol-enriched fraction, 19S AAA-ATPase expression was decreased in SZ. (C) In the nucleus-enriched fraction, trypsin-like activity was negatively correlated with both the constitutive and inducible catalytic subunits, (D) as well as the 19S RP subunits Rpt1 and Rpt2. (E) The 19S RP subunits Rpt3 and Rpt6 were positively correlated with chymotrypsin-like activity in the cytosol-enriched fraction. Center lines are Means ± S.E.M., *p < 0.05, **p < 0.01