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. 2019 Jul 25;2:274. doi: 10.1038/s42003-019-0526-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — BL23 EPS induced liver inflammation and injury in high-fat diet-fed zebrafish. Adult zebrafish (1-month-old) were fed with the control diet, high-fat diet (HFD), or HFD supplemented with 1% EPS for 4 weeks. Serum ALT (a) and serum AST (b) in zebrafsh. The expression of genes related to inflammation (c), pro-apoptotic factors (Noxa and Puma) and anti-apoptotic factors (Mcl-1a and Mcl-1b) (e) in livers as measured by q-PCR (n = 3, pool of three zebrafish per sample). d Representative liver histology images with TUNEL staining. The scale bar is 30 μm. Data were expressed as the mean ± SEM. Differences are considered significant at P < 0.05 (*) and P < 0.01 (**)