Fig. 5.

The liver injury effect of BL23 EPS involved the translocation of intestinal LPS. Adult zebrafish (1-month-old) were fed with control diet, high-fat diet (HFD), or HFD supplemented with 1.0%BL23 EPS or 1.0%LGG EPS for 4 weeks. The hepatic expression of TLRs genes (a), secreted PRRs (MBL, CRP, LBP) genes (b), and cytosolic PRRs (NODs) genes (c) in zebrafish livers as measured by q-PCR (n = 3 or 4, pool of three zebrafish per sample). Serum LPS (d) and hepatic LPS (e) in zebrafsh (n = 3 or 4, pool of three zebrafish per sample). Data are expressed as the mean ± SEM. Graph bars labelled with different letters on top represent statistically significant results (P < 0.05), whereas bars with the same letter correspond to results that show no statistically significant differences