Table 2.
Arm 1 (N = 101) |
Arm 2 (N = 72) |
Arm 3 (N = 102) |
Crude differences in cumulative incidence of PD9 | ||||
---|---|---|---|---|---|---|---|
i.v. carboplatin + i.v. paclitaxel |
i.p. cisplatin + i.v./i.p. paclitaxel |
i.p. carboplatin + i.v./i.p. paclitaxel |
|||||
N | % (95% CI) | N | % (95% CI) | N | % (95% CI) | % (95% CI) | |
Progression or death at or before Month 9 | 39 | 38.6 | 25 | 34.7 | 25 | 24.5 | |
(29.1 to 48.1) | (23.7 to 45.7) | (16.2 to 32.9) | |||||
Arm 1 versus arm 3 | 14.1 (1.5 to 26.7) | ||||||
Arm 2 versus arm 3 | 10.2 (−3.6 to 24.0) | ||||||
Time of event | |||||||
First relapse/progression on treatment | 0 | 1 | 0 | ||||
Objective progression only | 0 | 0 | 0 | ||||
CA125 progression only | 0 | 0 | 0 | ||||
Both objective and CA125 progressions | 0 | 1 | 0 | ||||
First relapse/Progression during follow-up | 39 | 24 | 24 | ||||
Objective progression only | 17 | 5 | 7 | ||||
CA125 progression only | 0 | 0 | 0 | ||||
Both objective and CA125 progressions | 22 | 19 | 17 | ||||
Death (without relapse/progression) | 0 | 0 | 1 |
i.p., intraperitoneal; i.v., intravenous.