(A,B) LINC01220 knockdown reduced proliferative ability of Ishikawa and RL95-2 cells, which was enhanced after co-transfection with sh-LINC01220 and pcDNA-MAPK11. (C) LINC01220 knockdown reduced colony formation ability of Ishikawa and RL95-2 cells, which was enhanced after co-transfection with sh-LINC01220 and pcDNA-MAPK11. (D) LINC01220 knockdown induced apoptosis of Ishikawa and RL95-2 cells, which was inhibited after co-transfection with sh-LINC01220 and pcDNA-MAPK11. *P<0.05, **P<0.01, ***P<0.001, #P<0.01 (vs. sh-LINC01220), #P<0.001 (vs. sh-LINC01220).