TABLE 7.
Metabolite | Proposed structure | % oDRM, single dose (25 mg), day 1, 0–24 h | % oDRM, repeat dose (15 mg), day 14, 0–24 h |
---|---|---|---|
P (GSK3036656) | 100 | 100 | |
M1 (GSK3635633), oxidation and deboronation | ND | ND |
oDRM, observed drug-related material; ND, not detected.