FIG 5.
(A) FTC accumulation in mock and MDCK-hOCTN1 cells in the absence or presence of quinidine.*, P < 0.05 versus mock cells; #, P < 0.05 versus no inhibitor. (B) Concentration-dependent profiles of FTC uptake in MDCK-hOCTN1. (C) MDCK-hOCTN1-mediated uptake was analyzed by means of the Eadie-Hofstee plot. (D) FTC accumulation in mock cells and MDCK-hOCTN2 cells in the absence or presence of l-carnitine (an inhibitor of OCTN2).