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The predicted placental transfer of FTC (schematic). ENT1, CNT1, and OCTN1 probably contribute to uptake of FTC from maternal circulation to trophoblasts, whereas BCRP and MRP1/2/3 facilitate FTC transport from trophoblasts to maternal circulation. ENT1, CNT1, and MRP1 are likely involved in FTC transport between trophoblasts, the placenta, and fetal blood.
