FIG 4.

Dose-response curves representing the effect of T-2307 on the enzymatic activities of respiratory chain complexes in Saccharomyces cerevisiae (a) and Candida albicans (b). The reaction rate of each enzyme was determined by calculating the slope of the linear portion of the curve representing the trace of the reaction of each complex. Percent control was calculated based on the slope in the control. The values represent the mean and standard deviation values of pooled data from two independent experiments, each performed in triplicate (total six replicates per group).