Table 5.
Frequency of update on the publicly available databases to report medicines shortages.
| Frequency of updating | Country | Organization in charge of database | Access | Frequency of update | Mandatory Reporting |
|---|---|---|---|---|---|
| High | Australia | Therapeutics Goods Administration | https://apps.tga.gov.au/prod/MSI/search | Daily | Yes |
| Belgium | Federal Agency of Medicines and Health Products | https://banquededonneesmedicaments.fagg-afmps.be/#/query/supply-problem-history/human | Daily (this is nominal frequency, which may be different) | Yes | |
| Canada | Bell Canada under contract with Health Canada | www.drugshortagescanada.ca/ | Daily | Yes | |
| Czech Republic | State Institute for drug control | http://www.sukl.eu/dodavky-leciv-se-zamerenim-na-lecive-latky | Daily | Yes | |
| Latvia | State Agency of Medicines (SAMLV) | https://www.zva.gov.lv//?id=781&lang=&top=334&sa=673 | Daily | Yes | |
| Portugal [1] | Portugal ANF - National Association of Pharmacies (ANF - Associação Nacional de Farmécias) | https://www.anfonline.pt/ | Daily | Yes | |
| Sweden | Swedish medical products agency | https://lakemedelsverket.se/OVRIGA-SIDOR/Restnoteringar/ | As soon as posible | Yes | |
| US | American Society of Health Systems Pharmacist - ASHP | https://www.ashp.org/drug-shortages/current-shortages | Daily | Not | |
| Medium | Austria | Austrian Medicines and Medical Devices Agency (AGES MEA) | www.basg.gv.at/news-center/news/news-detail/article/uebersichtsliste-vertriebseinschraenkungen-986/ | Weekly | |
| Hungary | National Institute of Pharmacy and Nutrition | https://www.ogyei.gov.hu/temporary_discontinuation_of_sale_/ | Weekly | Yes | |
| Italy | Italian Medicines Agency (AIFA—Agenzia Italiana del ármaco) | http://www.aifa.gov.it/content/carenze-e-indisponibilt%C3%A0 | Weekly | Yes | |
| Malta [1] | Ministry for Health (CPSU—Central Procurement and Supplies Unit) | https://health.gov.mt/en/cpsu/Pages/POYC-OOS.aspx | Weekly | Yes | |
| Norway | Norwegian Medicines Agency | https://legemiddelverket.no/legemiddelmangel/legemiddelmangel-og-avregistreringer-2017-rad-til-apotek-og-helsepersonell | Weekly | Yes | |
| Slovakia | The State Institute for Drug Control (SUKL) | http://www.sukl.sk/en/inspection/post-authorization-quality-control/export-of-medicinal-products/list-of-medicinal-products-for-which-they-were-issued-decisions-not-to-allow-the-export-from-slovak-republic?page_id=4006 | Weekly | Yes | |
| Spain [2] | Center for Information on Medicines Supply (in Spanish: Centro de Información sobre el Suministro de Medicamentos; CISMED) | http://www.portalfarma.com/Profesionales/consejoinforma/Paginas/Infarma-2016-CISMED.aspx | Weekly | Yes | |
| Switzerland [1] | Federal Office of Public Health | https://www.bag.admin.ch/bag/de/home/themen/mensch-gesundheit/biomedizin-forschung/heilmittel/sicherheit-in-der-medikamentenversorgung.html?_organization=317 | Weekly | Yes | |
| Switzerland [2] | Federal Office for national economic supply (FONES) | https://www.bwl.admin.ch/bwl/de/home.html | Weekly | Yes | |
| Switzerland [3] | Swissmedic (Swiss Agency for Therapeutic Products) | https://www.swissmedic.ch/marktueberwachung/00135/00136/00140/00142/index.html?lang=de | Weekly | Yes | |
| Switzerland [4] | Martinelli Consulting Switzerland | www.drugshortage.ch | Weekly | Not applicable (private and voluntary but highly effective initiative) | |
| Turkey | Turkish Medicines and Medical Devices Agency: TMMDA (in Turkish: Türkiye Ilaç Ve Tibbi Cihaz Kurumu; TİTCK) | http://www.titck.gov.tr/ | Weekly | Yes | |
| Low | Argentina | National Administration of Medicines, Food and Medical Technology (ANMAT) | https://www.argentina.gob.ar/faltante-de-medicamentos | Twice a month | Yes |
| Croatia | Croatian Health Insurance Fund | http://www.hzzo.hr/zdravstveni-sustav-rh/trazilica-za-lijekove-s-vazecih-lista/ | Monthly | Yes | |
| France [1] | French Agency for Medicines Safety (ANSM – Agence Nationale pour la Sécurité du Medicament) | http://ansm.sante.fr/Mediatheque/Publications/Information-in-English | Yearly | Yes | |
| France [2] | National Council of the College of Pharmacists (Conseil national de l’ordre national des pharmaciens – CNOP) | http://www.ordre.pharmacien.fr/Le-Dossier-Pharmaceutique/Ruptures-d-approvisionnement-et-DP-Ruptures | Monthly | Yes | |
| Lithuania | State Medicines Control Agency (SMCA) | www.vvkt.lt | Biweekly | Unspecified | |
| Greece | National Organization for Medicines (EOF) | http://www.eof.gr/web/guest/eparkeia | Monthly (this is usual frequency) | Yes | |
| Ireland [1] | Irish Pharmaceutical Union (IPU) | https://ipu.ie/home/ipu-product-file/medicine-shortages/ | Minimum monthly, but on demand based on completion of medicines shortages notification form | Yes | |
| Poland | Ministry of Health | http://www.bip.mz.gov.pl/legislacja/akty-prawne/obwieszczenie-ministra-zdrowia-z-dnia-10-stycznia-2017-r-w-sprawie-wykazu-produktow-leczniczych-srodkow-spozywczych-specjalnego-przeznaczenia-zywieniowego-oraz-wyrobow-medycznych-zagrozonych-brakiem/ | At least bimonthly | Yes | |
| Unspecified | Brazil | National Health Surveillance Agency (ANVISA) | http://portal.anvisa.gov.br/descontinuacao-de-medicamentos | As necessary (after every notification by MAH | Yes |
| Bulgary | Bulgarian Drug Agency | http://www.bda.bg/bg/ | As requiered | Not know | |
| Colombia [1] (may 2018 until now) |
National Institute of Food and Medicines Surveillance (INVIMA) | https://www.invima.gov.co/desabastecimiento-de-medicamentos | As required | Yes | |
| Colombia [2] (2012 until april 2018) |
Ministry of Health | https://www.minsalud.gov.co/salud/MT/Paginas/desabastecimiento.aspx | As required | Yes | |
| Denmark | Danish Medicines Agency | https://laegemiddelstyrelsen.dk/da/godkendelse/kontrol-og-inspektion/alvorlige-forsyningsvanskeligheder/# | As required | Yes | |
| Estonia | Estonian State Agency of Medicines | http://www.ravimiamet.ee/ulevaatlik-tabel-humaanravimite-tarneraskustest | As necessary (after every notification by MAH) | Yes | |
| Finland | The Finnish Medicines Agency - Fimea | https://www.fimea.fi/tietoa_fimeasta/ajankohtaista/saatavuushairiotiedotteet | As required | Yes | |
| Germany | Instituto Federal de Medicamentos y Dispositivos Médicos | https://www.bfarm.de/DE/BfArM/_node.html | As required | Yesit | |
| Israel | Ministry of Health | www.health.gov.il | According to the need | Yes | |
| Ireland [1] | UniPhar | www.uniphar.ie | As required | Yes | |
| Kosovo | Kosovo Medicines Agency | www.akppm.com | – | No | |
| Malta [1] | Ministry for Health (CPSU – Central Procurement and Supplies Unit) | https://health.gov.mt/en/cpsu/Pages/Items-Problematic-To-Source.aspx | As required | Yes | |
| Republic of Srpska, Bosnia and Herzegovina | The Agency for Medicinal Products and Medical Devices of Bosnia and Herzegovina (ALMBIH) | http://www.almbih.gov.ba/vijesti/ | As soon as the ALMBIH is informed by the MAH about shortage of a given medicine | Yes | |
| Romania | National Agency for Medicines and Medical Devices | https://www.anm.ro/en/ | As required | Yes | |
| Spain [1] | Spanish Agency of Medicines and Health Products (AEMPS), being part of the Spanish Ministry of Health | https://cima.aemps.es/cima/fichasTecnicas.do?metodo=buscarDesabastecidos | As required (whenever a shortage is detected) | Yes | |
| Slovenia | Agency for Medicinal Products and Medical Devices (JAZMP), and Health Insurance Institute of Slovenia |
http://www.jazmp.si/fileadmin/datoteke/seznami/SFE/Prisotnost/Seznam_44_HUM_prenehanja_motnje.pdf
www.cbz.si |
Irregular | Yes | |
| United Kingdom | Specialist pharmacy service | https://www.sps.nhs.uk/ | As needed | Yes | |
| Uruguay | Ministry of Public Health | https://tramites.gub.uy/ampliados?id=2659 | As needed | Yes | |
| US [2] | Food and Drug Administration | https://www.accessdata.fda.gov/scripts/drugshortages/ | Not specified | Not |