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. 2019 Jul 19;10:487. doi: 10.3389/fendo.2019.00487

Table 2.

Multivariate analysis using Cox proportional hazard ratio model for disease free survival (A) and overall survival (B) (HR, hazard ratio; CI, confidence interval).

A
Disease free survival covariates Cut off (category) HR 95%CI P-value
Age at diagnosis, years ≥61 (vs. <61) 1.507 0.648–3.502 0.341
Cortisol production Yes (vs. No) 2.248 1.139–4.435 0.020
ENSAT stage IV (vs. I, II, and III) 4.560 1.604–12.96 0.004
Cytoplasmic intensity of HSP90β <0.760(vs. ≥0.760) 2.574 1.183–5.598 0.017
B
Overall survival covariates Cut off (category) HR 95%CI P-value
Age at diagnosis, years ≥60 (vs. <60) 1.694 0.814–3.524 0.159
Cortisol production Yes (vs. No) 2.584 1.270–5.259 0.009
ENSAT stage IV (vs. I, II, and III) 7.676 3.314–17.78 <0.001
Cytoplasmic intensity of Hsp90β <0.760(vs. ≥0.760) 1.672 0.761–3.671 0.200