Figure 5.

Invadopodia: dynamic micro‐invasive structures. Invadopodia are generated from an actin‐cortactin core at the plasma membrane and are used by cancer cells to degrade the extracellular matrix locally to promote invasion. The protease MT1‐MMP is expressed on the thin, filopodia‐like processes, which can degrade the matrix proteins and structures that they touch [Colour figure can be viewed at wileyonlinelibrary.com]