. 2019 Aug;370(2):337–349. doi: 10.1124/jpet.119.257543

TABLE 3.

Model parameters for glucocorticoid-induced leucine zipper (GILZ) mRNA dynamics

Parameter	Definition	Estimate (% CV)
k_d,GILZm (h⁻¹)	Degradation rate constant for GILZ	7.5 (21.8)^a; 1.9 (27.5) ^b
S_max	Maximal stimulatory capacity by DR_N	7.5^a^,^b^,^c
SC_50,GILZm (fmol/mg)	DR_N producing half-maximal stimulation	558 (5.5)^a; 672 (19.2)^b
K_i (fmol/mg)	ER_N producing half-maximal inhibition of SC₅₀ of DR_N	62.1 (68.6)^a^,^b
GILZ_m(0) (molecules/ng of RNA)	GILZ initial concentration in liver	1893 (M); 2051 (E); 2538 (PE)
GILZ_m(0) (molecules/ng RNA)	GILZ initial concentration in uterus	3245 (E); 2400 (PE)

^{^a}

Liver.

^{^b}

Uterus.

^{^c}