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. 2019 Jul 19;10:1671. doi: 10.3389/fimmu.2019.01671

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Copyright © 2019 Gómez-Olarte, Bolaños, Echeverry, Rodríguez, Cuéllar, Puerta, Mariño and González.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytokines and chemokines concentration in plasma from donors of all groups. Heat map that shows the patterns of cytokines and chemokines concentration in chagasic patients (IND, CCC, and HTCC) and controls (NCC and HI) are distinct (A). Comparison of IL-1β, IL-1RA, IL-6, IL-12p40, IL-23, CXCL10, and CCL17 levels was done with Mann-Whitney test. The median and interquartile ranges of cytokines are displayed (B). ND, Not detectable. Differences are indicated as follows: ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001.