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Q331K inhibits DNA DSB repair. (A) Analysis of γH2AX foci kinetics after IR (3 Gy) treatment by IF microscopy. γH2AX foci are shown in green (Scale bar, 5 μm). Quantitation of the average number of foci per cell shown in histogram. (B) Time course comet analysis of cells treated with 3 Gy radiation. Quantitation of mean comet tail moment in 50 randomly selected cells (Scale bar, 10 μm). **P<0.05 ; ****P<0.0001.
