Table 4.

Results from the Mixed Effects Meta Analyses examining the relationships between scores on the Pain Catastrophizing Scale and brain responses during pain processing and cognitive modulation of pain for FM (N = 16)

Pain During Congruent Stroop
Group	Brain Regions	Peak X, Y, X	Volume, mm3	Peak t-Statistic
FM	L PFC	40, −56, 6	9,984	6.38
FM	R PFC	−36, −60, 10	7,360	5.97
Pain During Incongruent Stroop
Group	Brain Regions	Peak X, Y, X	Volume, mm3	Peak t-Statistic
FM	R PFC	−40, −60, 2	6,592	5.63

Included in the table are clusters showing significant relationships between total scores on the PCS and brain responses associated with cognitive modulation of pain during the Stroop color-word tasks, controlling for scores on the Beck Depression Inventory. All clusters represent positive relationships. For each analysis, multiple comparisons were corrected for using a cluster-size threshold of 65 voxels or 4,570 mm³. There were no significant regions for CO (N = 15).

FM = fibromyalgia; L = left; PFC = prefrontal cortex; R = right.