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. 2018 Aug 24;166(2):288–305. doi: 10.1093/toxsci/kfy198

Figure 8.

Figure 8.

Flow cytometry assessment of circulating leukocyte subpopulations after ozone exposure in SH and AD rats treated with vehicle or CLEN+DEX. Percentage of circulating leukocyte subpopulations CD4-CD8a− (A), CD4−CD8a+ (B), CD4+CD8a− (C), and CD4+CD8a+ (D) were determined following air or ozone (0.8 ppm) exposure (4 h/day) for D + 1 groups. Cells positive for CD4−CD8a+, CD4+CD8a−, and CD4+CD8a+ were considered T-lymphocyte subpopulations. Relative numbers were determined based on CD45+ cells (total leukocytes). Bar graphs show mean ± SEM of n = 6–8/group. Significant differences between groups (p-value ≤ .05) are indicated by * for ozone effect when compared with corresponding air-exposed rats, # for AD effect when compared with corresponding SH rats, and † for CLEN+DEX effect when compared with corresponding vehicle-treated rats.