Table I.
Baseline status of the study subjects.
| Variables | A1 Diabetes for <5 year without microalbuminuria (n=30) | A2 Diabetes for 5-10 year with microalbuminuria (n=30) | B Controls (n=25) | p-value |
|---|---|---|---|---|
| Age (Years) | 45.70±10.27^ | 46.72±13.37# | 29.8±6.4 | <0.001 |
| Weight (kg) | 69.16±11.44 | 70.96±16.51 | 61.86±7.08 | 0.049 |
| BMI (kg/m2) | 27.34±5.59^ | 28.21±5.94# | 22.81±2.69 | 0.003 |
| Hemoglobin (mg/dL) | 12.01±0.98* | 10.76±1.87 | 11.23±0.53 | 0.005 |
| HbA1c | 7.286±0.74^ | 7.43±1.03# | 5.18±0.27 | 0.031 |
| FBG at baseline (mg/dl) | 136.77 + 45.19*,^ | 172.44 ± 38.32# | 87.86 ± 9.08 | 0.031 |
| FBG at 6 months (mg/dl) | 172.45 ± 62.56^ | 190.66 ± 71.65# | 79.55 ± 8.64 | 0.000 |
| RBG at baseline (mg/dl) | 163.77 ± 41.46* | 202.71 ± 58.38# | 156.66 ±58.06 | 0.007 |
| RBG at 6 months (mg/dl) | 150.81 ± 27.35* | 233.85 ± 94.86# | 158.22 ± 32.15 | 0.005 |
| Blood Urea nitrogen (mg/dL) | 11.79±2.75* | 25.50±2.12# | 12.67±3.47 | 0.000 |
| Serum urea (mg/dL) | 35.56±7.19*,^ | 57.30±35.03# | 27.11±7.42 | 0.000 |
| Serum Creatinine (mg/dL) | 0.73±0.17* | 1.34±0.90# | 0.84± 0.12 | 0.000 |
| Serum Sodium (mmol/liter) | 139.46±2.75 | 134.26±8.48 | 132.21±5.44 | 0.05 |
| Serum Potassium (mmol/liter) | 4.36±0.51 | 3.87±0.84 | 3.95±0.45 | 0.05 |
Values expressed as Mean ± SD. Comparison between groups was made by ANOVA with Tukey’s b applied as a posthoc test analysis.
*
A1compared with A2;
^
A1 compared with B;
#
A2 compared with B where statistically significant value was set at p<0.05