Table II.
Differences according to etiology of hypopituitarism.
| Characteristics | Sheehan’s Syndrome N=15 (35.7%) | Others N=27 (64.3%) | P-Value |
|---|---|---|---|
| Age groups (years) | |||
| 18-35 | 3 (20.0) | 2 (7.4) | 0.22 |
| 36-55 | 7 (46.7) | 9 (33.3) | |
| 56 and above | 5 (33.3) | 16 (59.3) | |
| Gender | |||
| Men | 0(0) | 5(18.5) | 0.07 |
| Women | 15(100) | 22(81.5) | |
| Duration of Illness, mean (SD) (months) | 42.8 (35.9) | 58.6 (69.8) | 0.42 |
| Decreased Libido | 13 (86.7) | 17 (63.0) | 0.10 |
| Infertility | 8 (53.3) | 8 (30.8) | 0.15 |
| Decreased Body Hair | 10 (66.7) | 15 (55.6) | 0.48 |
| Diminished sense of well being | 15 (100) | 25 (92.6) | 0.28 |
| Weakness | 15 (100) | 26 (96.3) | 0.45 |
| Hyponatremia | 9 (60) | 21 (77.8) | 0.22 |
| Hypoglycemia | 4 (26.7) | 2 (7.4) | 0.08 |
| Hypotension | 6 (40.0) | 6 (22.2) | 0.22 |
| Eosinophilia | 2 (13.3) | 3 (11.1) | 0.83 |
| Fatigue | 14 (93.3) | 24 (88.9) | 0.63 |
| Weight loss | 12 (80.0) | 17 (63.0) | 0.25 |
| Lethargy | 14 (93.3) | 24 (88.9) | 0.63 |
| Cold intolerance | 9 (60.0) | 11 (40.7) | 0.23 |
| Decreased appetite | 14 (93.3) | 22 (81.5) | 0.29 |
| Constipation | 5 (33.3) | 7 (25.9) | 0.611 |
| Facial Puffiness | 3 (20.0) | 4 (14.8) | 0.66 |
| Bradycardia | 0 (0) | 1 (3.7) | 0.45 |
| Anemia | 7 (46.7) | 13 (48.1) | 0.92 |
| Headache | 4 (26.7) | 9 (33.3) | 0.65 |
| Visual Disturbance | 0 (0) | 3 (11.1) | 0.18 |
| Altered Level of consciousness | 10 (66.7) | 10 (37.0) | 0.06 |
| Seizures | 2 (13.3) | 4 (14.8) | 0.89 |
| Arrhythmia | 1 (6.7) | 3 (11.1) | 0.63 |
| Body Mass Index, mean(SD) | |||
| Underweight (≤ 18.4) | 3 (25.0) | 4 (22.2) | 0.52 |
| Acceptable (18.5-22.9) | 3 (25.0) | 3 (16.7) | |
| Overweight (23-24.9) | 3 (25.0) | 2 (11.1) | |
| Obese (25 and above) | 3 (25.0) | 9 (50.0) | |
| Gonadotrophic deficiency | 14 (93.3) | 20 (74.1) | 0.12 |
| ACTH deficiency | 14 (93.3) | 27 (100) | 0.17 |
| TSH deficiency | 15 (100) | 27 (100) | - |
| Growth hormone deficiency | 14 (93.3) | 26 (96.3) | 0.66 |
| Prolactin Deficiency | 7 (46.7) | 6 (22.2) | 0.10 |
| Heart rate, mean(SD) (rates/min) | 84.2 (13.1) | 76.2 (9.3) | 0.04 |
| Blood pressure, systolic, mean(SD) (mmHg) | 135.4 (28.2) | 123.3 (22.4) | 0.16 |
| Blood pressure, diastolic, mean(SD) (mmHg) | 73.4 (12.6) | 72.6 (10.9) | 0.83 |
| Weight, mean(SD) (Kg) | 52.5 (12.6) | 59.6 (15.5) | 0.17 |
| Height, mean(SD) (cm) | 153.4 (6.0) | 155.8 (7.8) | 0.37 |
†SD: Standard deviation.