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. Author manuscript; available in PMC: 2019 Jul 26.
Published in final edited form as: Cell Cycle. 2010 May 15;9(9):1830–1838. doi: 10.4161/cc.9.9.11543

Table 1.

Neuroblastoma Cell Lines

Cell Line Chromosomal Alteration NMA* p53 Alk IC50 (ng/ml) IC80 (ng/ml) Ref
IMR32 1p LOH + wt wt 1 2 22
SK-N-BE(2) 1p LOH, t(3,17)(p21,q21) + mt wt 6.3 30 18
SMS-KCNR 1p LOH, t(17,20)(p21,q13) + wt mt, R1275Q 2 5 17
SK-N-AS 1p del, 1p(36.33) − wt wt 1.8 30 20
SH-SY5Y 1p LOH − wt mt, F1174L 5 30 19
SH-SHEP 1p LOH − wt mt, F1174L 1 4 22
LA1–15N 1p LOH + mt mt, F1174L 1.2 10 21
*

NMA-MYCN amplified; LOH= loss of hterozygosity; wt=wild-type; mt=mutant