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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Acta Biomater. 2019 May 3;94:204–218. doi: 10.1016/j.actbio.2019.04.057

Table 3. Toxicological risk assessment, component extraction.

GC-MS: Gas Chromatography-Mass Spectrometry, LC-MS: Liquid Chromatography-Mass Spectrometry, ICP-MS: Inductively Coupled Plasma Mass Spectrometry, HS-GC-MS: Headspace Gas Chromatography-Mass Spectrometry, MOS: Margin of safety.

Assay 100% exposure in 24 hrs 100% exposure over 30 days
GC-MS in hexane extracts Negative N/A
GC-MS in IPA/water extracts Negative N/A
GC-MS in water extracts Negative N/A
LC-MS in hexane extracts Negative N/A
LC-MS in IPA/water extracts 27 negative, 1 positive* Negative
LC-MS in water extracts 19 negative, 1 positive* Negative
ICP-MS Negative N/A
HS-GC-MS Negative N/A
*

Trimethylolpropane monoacrylate, MOS < 1.