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. 2019 Jul 19;10:819. doi: 10.3389/fphar.2019.00819

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Copyright © 2019 Xu, Chen, Ma, Liu, Zhao, Wang and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Score plot of the PLS-DA model (A) and the OPLS-DA model (B) based on UV scaling for ALF subject (red dots) and NLF (black dots) separation. (C) Cross-validation plot of PLS-DA mode with 200 times permutation tests. (D) Number of detected lipids based on a nontargeted lipidomics strategy in patient serum.