Table 4. Metaregression of Survey Data Submitted to the Food and Drug Administration by Trials Granted an Exception From Informed Consent.
| Metaregression Variable | OR (95% CI)a | P Value |
|---|---|---|
| Personal: 85 Aggregates, 27 579 Participants | ||
| Intercept | 5.827 (3.058-11.102) | <.001 |
| African American race | 0.914 (0.824-1.013) | .09 |
| Male sex | 0.840 (0.739-0.955) | .008 |
| Convenience sampling | 3.146 (2.170-4.561) | <.001 |
| Family: 58 Aggregates, 4003 Participants | ||
| Intercept | 4.420 (1.368-14.280) | .01 |
| African American race | 0.820 (0.717-0.937) | .004 |
| Male sex | 0.838 (0.713-0.984) | .03 |
| Convenience sampling | 6.044 (1.973-18.517) | .002 |
| Community: 59 Aggregates, 12 371 Participants | ||
| Intercept | 8.904 (5.016-15.804) | <.001 |
| African American race | 0.870 (0.790-0.958) | .004 |
| Male sex | 0.888 (0.792-0.996) | .04 |
| Convenience sampling | 2.465 (1.766-3.442) | <.001 |
| General: 16 Aggregates, 14 427 Participants | ||
| Intercept | 4.325 (1.253-14.931) | .02 |
| African American race | 0.703 (0.570-0.866) | .001 |
| Male sex | 1.022 (0.810-1.290) | .86 |
| Convenience sampling | 0.576 (0.354-0.935) | .03 |
Abbreviation: OR, odds ratio.
a
Odds ratios are for a 10% difference in African American race and male sex.