Table. Baseline Characteristicsa.
| Characteristic | Primary Analysis Population (N = 3049) |
|---|---|
| Demographics | |
| Age, years (median [25th, 75th]) | 65 (55, 75) |
| Female | 1132 (37.1) |
| Individuals of color, No. (%) | 797 (31.4) |
| BMIb (median [25th, 75th]) | 28.0 (24.1, 32.9) |
| General Medical Problems and Risk Factors | |
| Smoking status | |
| Current | 572 (19.0) |
| Ex-smoker | 1106 (36.7) |
| Unknown | 254 (8.4) |
| Hypertension | 1997 (65.5) |
| Diabetes | 1062 (34.8) |
| Chronic kidney disease | 736 (24.1) |
| Dialysis-dependent (% of total) | 170 (5.6) |
| Significant pulmonary disease | 432 (14.2) |
| Significant liver disease | 97 (3.2) |
| Significant dementia | 55 (1.8) |
| Active cancer | 202 (6.6) |
| Cardiovascular History | |
| Coronary artery disease | 1267 (41.6) |
| Cerebrovascular disease | 300 (9.8) |
| Peripheral artery disease | 288 (9.4) |
| Heart failure | 1103 (36.2) |
| HFrEF (EF, <40%) (% of total) | 677 (22.2) |
| Heart transplant | 45 (1.5) |
| Atrial fibrillation | 712 (23.4) |
| Ventricular arrhythmia | 183 (6.0) |
| Severe valvular disease | 427 (14.0) |
| Pulmonary hypertension | 125 (4.1) |
| Congenital heart disease | 57 (1.9) |
Abbreviations: BMI, body mass index; EF, ejection fraction; HFrEF, heart failure with reduced ejection fraction.
a
All data are reported as number (percentage) unless otherwise specified. Past noncardiovascular medical conditions were captured as “significant” based on the clinical judgment of the local investigators.
b
Calculated as weight in kilograms divided by height in meters squared.