Table 1.
Cox regression analysis correlating MCL-1 expression H-score and other clinicopathologic variables with patients’ overall survival.
| Univariate analysis |
Multivariate analysis |
|||||||
|---|---|---|---|---|---|---|---|---|
| p | Hazard ratio | 95% confidence interval | p | Hazard ratio | 95% confidence interval | |||
| Age | 0.50 | 0.99 | 0.95 | 1.02 | ||||
| Histology grade (poor or undiff) | 0.63 | 0.85 | 0.44 | 1.63 | ||||
| ypT stage (pT3–T4) | 0.36 | 1.38 | 0.69 | 2.74 | ||||
| ypN stage (pN1–3) | 0.01 | 2.41 | 1.21 | 4.79 | 0.23 | 1.57 | 0.75 | 3.29 |
| Pathologic response (P2) | 0.13 | 1.71 | 0.86 | 3.39 | 0.28 | 1.49 | 0.73 | 3.06 |
| Therapy for recurrence or progression | 0.00 | 3.99 | 1.99 | 8.01 | 0.00 | 3.56 | 1.73 | 7.34 |
| MCL-1 H-score ⩾40 | 0.02 | 2.32 | 1.18 | 4.56 | 0.01 | 2.38 | 1.19 | 4.72 |