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. 2019 Jul 25;19:194. doi: 10.1186/s12935-019-0913-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Screen of differentially expressed lncRNAs in papillary thyroid cancer. a Heatmap of differentially expressed lncRNAs (8 upregulated and 23 downregulated) in 3 papillary thyroid cancer tissues compared with matched normal tissues. b Volcano plots were constructed based on sequencing results of differentially expressed lncRNAs between papillary thyroid cancer tissues and normal tissues from 3 patients. The red points represent differentially upregulated genes, and green points represent downregulated genes. Arrow indicated MIAT in the plots. c RT-qPCR was performed to validate 6 differentially expressed lncRNAs (2 upregulated and 4 downregulated) obtained from sequencing of papillary thyroid cancer tissues and normal tissues of 3 patients. *p < 0.05; **p < 0.01; ***p < 0.001