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. 2019 Jul 25;19:194. doi: 10.1186/s12935-019-0913-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Silencing of MIAT inhibits cell proliferation, cycle and invasion ability of papillary thyroid cancer cells. a Transfection of MIAT siRNA1 or MIAT siRNA2 reduced MIAT expression in HTH83 and BHT101 cells. b Silencing of MIAT inhibited cell proliferation of HTH83 cells in a cell proliferation assay. c Silencing of MIAT inhibited cell proliferation of BHT101 cells in a cell proliferation assay. d The cell cycle analysis showed that MIAT silencing induced accumulation of HTH83 cells in G2/M phase. e Quantitative analysis of HTH83 cells enriched in G1, S and G2/M phase in d. f The cell cycle analysis showed that MIAT silencing induced accumulation of BHT101 cells in G2/M phase. g Quantitative analysis of BHT101 cells enriched in G1, S and G2/M phase in f. h Silencing of MIAT inhibited cell invasion of HTH83 cells in a cell invasion assay. i Silencing of MIAT inhibited cell invasion of BHT101 cells in a cell invasion assay. *p < 0.05; **p < 0.01; ***p < 0.001