Table 1.
Hazard and hazard category classifications of chemicals reported by Vardavas et al. and their corresponding FEMA numbers
| Substance | FEMA GRAS No | Hazard, hazard category and hazard phrase according to CLP | Reference |
|---|---|---|---|
| Menthol | 2265 | H315 Causes skin irritation (Category 2) | [16] |
| H319 Causes serious eye irritation (Category 2) | |||
| Ethyl maltol | 3487 | H302 Harmful if swallowed (Category 4) | [15] |
| Linalool | 2635 | H315 Causes skin irritation (Category 2) | [17] |
| H317 May cause an allergic skin reaction. (Category 1) | |||
| H319 Causes serious eye irritation (Category 2) | |||
| Methyl cyclopentenolone | 2700 | H302 Harmful if swallowed (Category 4) | [18] |
| H319 Causes serious eye irritation (Category 2) | |||
| H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled (Category 1) | |||
| H335 May cause respiratory irritation (Category 3) | |||
| β-Damascone | 3243 | H317 May cause an allergic skin reaction. (Category 1) | [19] |
| H411 Toxic to aquatic life with long-lasting effects (Category 2) | |||
| Ethyl vanillin | 2464 | H302 Harmful if swallowed (Category 4) | [20] |
| H315 Causes skin irritation (Category 2) | |||
| H319 Causes serious eye irritation (Category 2) | |||
| H335 May cause respiratory irritation (Category 3) | |||
| H412 Harmful to aquatic life with long-lasting effects (Category 3) | |||
| β-Ionone | 2595 | H400 Very toxic to aquatic life (Category 1) | [21] |
| H411 Toxic to aquatic life with long-lasting effects (Category 2) | |||
| Acetyl pyrazine | 3126 | H315 Causes skin irritation (Category 2) | [22] |
| H319 Causes serious eye irritation (Category 2) | |||
| H335 May cause respiratory irritation (Category 3) | |||
| α-Ionone | 2594 | H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled (Category 1) | [23] |
| H412 Harmful to aquatic life with long-lasting effects (Category 3) | |||
| Ethyl hexanoate | 2439 | H226 Flammable liquid and vapour (Category 3) | [24] |
| 2,5 dimethylpyrazine | 3271 | H226 Flammable liquid and vapour (Category 3) | [25] |
| H302 Harmful if swallowed (Category 4) | |||
| α-Damascone | 4088 | H302 Harmful if swallowed (Category 4) | [26] |
| H317 May cause an allergic skin reaction (Category 1) | |||
| H411 Toxic to aquatic life with long-lasting effects (Category 2) | |||
| 3,4 Dimethoxy-benzaldehyde | 3109 | H302 Harmful if swallowed (Category 4) | [27] |
| Limonene | 2633 | H226 Flammable liquid and vapour (Category 3) | [28] |
| H304 May be fatal if swallowed and enters airways (Category 1) | |||
| H315 Causes skin irritation (Category 2) | |||
| H317 May cause an allergic skin reaction (Category 1) | |||
| H400 Very toxic to aquatic life (Category 1) | |||
| H410 Very toxic to aquatic life with long-lasting effect (Category 1) |