Table 1.
Distribution of social, health and clinical patient’s variables by age groups in stage III colon cancer (n = 654)
| N | < 65 years N = 246 n (%) |
65–80 years N = 311 n (%) |
> 80 years N = 97 n (%) |
P valuea | |
|---|---|---|---|---|---|
| Sociodemographic variables | |||||
| Sex | 654 | ||||
| Male | 151 (61.4) | 205 (65.9) | 60 (61.9) | 0.50 | |
| Female | 95 (38.6) | 106 (34.1) | 37 (38.1) | 0.65 | |
| Deprivation index | 624 | ||||
| Quartile 1 least deprived | 49 (21.2) | 67 (22.3) | 17 (18.5) | 0.67 | |
| Quartile 2 | 64 (27.7) | 101 (33.6) | 31 (33.7) | 0.78 | |
| Quartile 3 | 67 (29.0) | 72 (23.9) | 22 (23.9) | ||
| Quartile 4 most deprived | 51 (22.1) | 61 (20.3) | 22 (23.9) | ||
| Level of education | 534 | ||||
| Illiterate or with no formal education | 10 (4.8) | 46 (18.2) | 15 (20.5) | < 0.0005 | |
| Primary | 123 (59.1) | 162 (64.0) | 50 (68.5) | < 0.0005 | |
| Secondary | 35 (16.8) | 24 (9.5) | 3 (4.1) | ||
| University | 40 (19.2) | 21 (8.3) | 5 (6.8) | ||
| Living arrangements | 522 | ||||
| Living alone | 23 (11.5) | 42 (17.0) | 14 (18.7) | 0.18 | |
| Living with others | 177 (88.5) | 205 (83.0) | 61 (81.3) | 0.08 | |
| Family history of cancer | 584 | ||||
| No | 118 (52.2) | 175 (63.9) | 68 (81.0) | < 0.0005 | |
| Yes | 108 (47.8) | 99 (36.1) | 16 (19.0) | < 0.0005 | |
| Screening | 622 | ||||
| No | 174 (74.0) | 250 (84.7) | 86 (93.5) | < 0.0005 | |
| Yes | 61 (26.0) | 45 (15.3) | 6 (6.5) | < 0.0005 | |
| Health behaviours and comorbidities | |||||
| Smoking habits | 648 | ||||
| Never smoker | 112 (45.5) | 154 (50.0) | 50 (53.2) | 0.01 | |
| Current smoker | 42 (17.1) | 31 (10.1) | 4 (4.3) | 0.79 | |
| Ex-smoker | 92 (37.4) | 123 (39.9) | 40 (42.6) | ||
| Alcohol | 612 | ||||
| No | 188 (83.9) | 257 (86.2) | 84 (93.3) | 0.09 | |
| Yes | 36 (16.1) | 41 (13.8) | 6 (6.7) | 0.04 | |
| ASA class | 633 | ||||
| I-II | 175 (73.2) | 157 (52.2) | 30 (32.3) | < 0.0005 | |
| III | 60 (25.1) | 127 (42.2) | 52 (55.9) | < 0.0005 | |
| IV | 4 (1.7) | 17 (5.6) | 11 (11.8) | ||
| Charlson Index | 654 | ||||
| 0 | 163 (66.3) | 158 (50.8) | 40 (41.2) | < 0.0005 | |
| 1 | 49 (19.9) | 80 (25.7) | 26 (26.8) | < 0.0005 | |
| ≥ 2 | 34 (13.8) | 73 (23.5) | 31 (32.0) | ||
| Tumour characteristics | |||||
| Site | 654 | ||||
| Rectosigmoid junction | 40 (16.3) | 45 (14.5) | 11 (11.3) | 0.72 | |
| Distal colon | 108 (43.9) | 140 (45.0) | 41 (42.3) | 0.21 | |
| Proximal colon | 98 (39.8) | 126 (40.5) | 45 (46.4) | ||
| Histological classification | 643 | ||||
| Adenocarcinoma | 219 (91.3) | 274 (89.3) | 87 (90.6) | 0.18 | |
| Mucinous adenocarcinoma | 16 (6.7) | 27 (8.8) | 9 (9.4) | 0.69 | |
| Signet-ring cell carcinoma | 2 (0.8) | 6 (2.0) | 0 (0.0) | ||
| Other types of carcinoma | 3 (1.3) | 0 (0.0) | 0 (0.0) | ||
| Degree of differentiation | 573 | ||||
| Low grade | 165 (79.3) | 226 (81.9) | 79 (88.8) | 0.15 | |
| High grade | 43 (20.7) | 50 (18.1) | 10 (11.2) | 0.07 | |
| Intervention | |||||
| Main intervention | 654 | ||||
| Elective | 232 (94.3) | 300 (96.5) | 87 (89.7) | 0.03 | |
| Emergency | 14 (5.7) | 11 (3.5) | 10 (10.3) | 0.32 | |
| Curative resection | 618 | ||||
| R0 | 218 (92.4) | 261 (90.0) | 84 (91.3) | 0.63 | |
| R1 / R2 | 18 (7.6) | 29 (10.0) | 8 (8.7) | 0.56 | |
| Surgeon’s profile | 615 | ||||
| General | 61 (27.0) | 96 (32.5) | 36 (38.3) | 0.12 | |
| Coloproctologist | 165 (73.0) | 199 (67.5) | 58 (61.7) | 0.04 | |
| Cancer committee | 617 | ||||
| No | 77 (32.9) | 127 (43.6) | 44 (47.8) | 0.01 | |
| Yes | 157 (67.1) | 164 (56.4) | 48 (52.2) | 0.004 | |
aPearson Chi-square test to generate upper P value and chi-square test for trends to generate lower P value