Table 4.

Crude and adjusted analysis of the association between age and preoperative radiotherapy in stage II and III rectal cancer patients

	Preoperative radiotherapy in stage II and III rectal cancer
	4A. Univariate analysis		4B. Multivariate analysis
	n (%)	P value	Odds Ratio (95% CI)	P value
Age, years
< 65	138 (68.0)	< 0.0005b	1
65–80	142 (60.4)		0.9 (0.6–1.4)	0.74
> 80	27 (42.2)		0.5 (0.3–0.8)	0.004
Sex
Male	205 (60.7)	0.85a
Female	102 (61.8)
Deprivation index
Quartile 1	50 (61.7)	0.31b
Quartile 2	86 (54.8)
Quartile 3	94 (61.8)
Quartile 4	57 (65.5)
Level of education
No formal	31 (62.0)	0.78b
Primary	164 (60.5)
Secondary	28 (65.1)
University	25 (55.6)
Living arrangements
Living alone	30 (60.0)	0.88a
Living with others	217 (61.3)
Family history of cancer
No	147 (55.3)	0.005a	1
Yes	136 (68.3)		1.5 (1.0–2.1)	0.05
Screening
No	262 (61.6)	0.30a
Yes	29 (53.7)
Smoking habits
Never smoker	136 (60.7)	0.31a
Current smoker	56 (68.3)
Ex-smoker	113 (58.5)
Alcohol
No	264 (61.4)	0.77a
Yes	32 (59.3)
Charlson index
0	179 (64.6)	0.03b	1
1	74 (60.7)		0.9 (0.6–1.4)	0.77
≥ 2	54 (51.9)		0.9 (0.5–1.7)	0.88
ASA class
I-II	187 (63.8)	0.12b	1
III	106 (57.6)		0.9 (0.6–1.2)	0.39
IV	7 (50.0)		0.8 (0.3–2.4)	0.68
Degree of differentiation
Low grade	201 (59.5)	0.76a
High grade	29 (56.9)
Histological classification
Adenocarcinoma	268 (60.8)	0.29a
Mucinous adenocarcinoma	13 (52.0)
Stage
II	75 (45.7)	< 0.0005a	1
III	232 (68.4)		2.8 (1.5–4.9)	0.001
Cancer committee
No	84 (57.9)	0.48a
Yes	205 (61.6)
Surgeon’s profile
General	91 (61.1)	1.0a
Coloproctologist	201 (61.3)

^aPearson Chi-square test

^bChi-square test for trends