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. 2019 Jul 25;17:243. doi: 10.1186/s12967-019-1990-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Scanning electron microscopy (SEM) images of a P. aeruginosa hpBIOMs. a Within the biofilm, bacteria were attached in close vicinity on the surface of the matrix, to develop microcolonies (arrows, dotted lines). b One h after supplementation of L. plantarum, probiotics arrive the colonies (arrows, straight lines), production of the EPS and scattered interactions were visible. c After 4 h, L. plantarum has produced a strong glycokalyx, which seemed to cover and subsequently destroy Pseudomonas