Table 1.

Polyethylene glycol (PEG)-derivatized anticancer drug as dual-functional micellar carrier.

Self-assembled prodrugs	Hydrophobic drug	Co-loaded drug	In vitro/in vivo experimental model	References
CPT-SS-PEG-SS-CPT	Camptothecin	Camptothecin	HepG2 human hepatoma cell model	(Li et al., 2011)
CPT-PEG-CPT	Camptothecin	Doxorubicin	Human cervical cancer Hela cells	(Dong et al., 2012)
mPEG-BC-PGluCPT	Camptothecin	Doxorubicin	HepG2 and HL-7702 cells	(Gao et al., 2018)
P(CPTMA-coPEMA)	Camptothecin	Glucose oxidase	A549 tumors	(Li et al., 2017)
PEG-bPTCPT	Camptothecin	β-lapachone	Mouse breast cancer 4T1 cell line and 4T1 tumor-bearing mice	(Yin et al., 2019)
PEG-PTX	Paclitaxel	Paclitaxel	MCF-7 cells and mouse xenograft tumor model bearing MCF-7 cells	(Lu et al., 2014a)
PEG-acetal-PTX	Paclitaxel	Paclitaxel	HeLa and MDA-MB-231 cells	(Huang et al., 2018)
mPEG-b-DOX	Doxorubicin	Verapamil	MCF-7/ADR cell line	(Zhao et al., 2015)
PEG-CH = N-DOX	Doxorubicin	7-ethyl-10-hydroxyl-camptothecin	MCF-7 cells and mouse xenograft tumor model bearing MCF-7 cells	(Sun et al., 2018b)
PEG–DTX	Docetaxel	Docetaxel	H460 human non-small cell lung, SKOV-3 human ovarian and MCF-7 human breast cancer cells	(Liu et al., 2008)
PEG-CCM@APTES-COF-1	Curcumin	Doxorubicin	HeLa cells and HeLa cell xenograft tumor mice model	(Zhang et al., 2018a)
PEG-Fmoc-GA	Glycyrrhizic acid	Doxorubicin	HepG2 cells human liver cancer xenograft model	(Yang et al., 2018b)