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. 2019 Jun 18;48(3):822–830. doi: 10.1093/ije/dyz113

Table 1.

Associations between genetically predicted PCOS and ovarian cancer overall and by histotype using 14 SNPs associated with PCOS in European ancestry populations

IVW method
Cochran Q statistic
Odds ratio (95% CI) P-value Test statistic P-value
Borderline 1.08 (0.94–1.25) 0.27 7.66 0.86
 Serous 1.06 (0.89–1.27) 0.52 12.32 0.50
 Mucinous 1.13 (0.90–1.41) 0.29 10.92 0.62
Invasive 0.92 (0.85–0.99)  0.03  17.31 0.19
 Low-grade serous 1.09 (0.83–1.43) 0.53 16.26 0.24
 High-grade serous 0.91 (0.82–0.998) 0.046 18.71 0.13
 Mucinous 1.13 (0.92–1.38) 0.25 12.08 0.52
 Endometrioid 0.77 (0.65–0.92) 0.003 18.69 0.13
 Clear cell 0.90 (0.73–1.10) 0.30 12.00 0.53