Table 2.
Liver Functional Assessment Parameters
| Non‐LC | LC | |||||||
|---|---|---|---|---|---|---|---|---|
| Time (hours) | 0 | 2 | 4 | 6 | 0 | 2 | 4 | 6 |
| Lactate, mmol/L | 13.7 (4.1) [7.2‐20.0] | 14.6 (5.7) [4.4‐20.0] | 13.7 (4.5) [9.2‐20.0] | 14.6 (5.7) [6.9‐20.0] | 10.5 (3.3) [5.5‐13.9] | 3.0 (1.7) [0.6‐5.5] | 2.1 (1.1) [0.7‐4.0] | 2.1 (1.1) [0.7‐3.1] |
| Glucose, mmol/L | 49.3 (9.7) [37.2‐64.1] | 50.5 (9.7) [39.5‐64.5] | 40.3 (12.4) [26.2‐60.3] | 34.1 (15.2) [15.1‐56.2] | 36.4 (18.3) [9.3‐56.6] | 41.3 (12.9) [23.3‐59.3] | 34.1 (14.8) [14.2‐56.7] | 29.6 (20.2) [8.0‐52.4] |
| pH | 7.3 (0.5) [6.8‐8.0] | 7.3 (0.3) [6.8‐7.8] | 7.4 (0.4) [6.9‐7.8] | 7.4 (0.2) [7.2‐7.8] | 7.2 (0.2) [6.9‐7.5] | 7.3 (0.1) [7.2‐7.4] | 7.4 (0.1) [7.3‐7.6] | 7.4 (0.1) [7.3‐7.6] |
| Arterial flow, mL/minute | 213.8 (238.5) [11.0‐593.0] | 316.3 (224.4) [103.0‐631.0] | 412.6 (269.7) [98.0‐810.0] | 495.2 (330.8) [136.0‐835.0] | 155.0 (96.2) [58.0‐313.0] | 524.2 (118.8) [426.0‐727.0] | 575.2 (43.1) [527.0‐638.0] | 621.2 (52.1) [550.0‐682.0] |
| Arterial flow rate (mL/minute/g) | 0.1 (0.1) [0.01‐0.5] | 0.2 (0.1) [0.1‐0.3] | 0.2 (0.1) [0.1‐0.4] | 0.3 (0.2) [0.1‐0.5] | 0.1 (0.05) [0.03‐0.2] | 0.3 (0.1) [0.2‐0.4] | 0.3 (0.1) [0.2‐0.4] | 0.3 (0.1) [0.3‐0.4] |
| Portal flow, mL/minute | 613.3 (177.7) [470.0‐910.0] | 962.5 (261.5) [690.0‐1250.0] | 1120.0 (70.7) [1030.0‐1210.0] | 1158.0 (125.2) [970.0‐1320.0] | 458.3 (166.8) [210.0‐630.0] | 1176.0 (192.3) [1000.0‐1430.0] | 1330.0 (225.1) [1100.0‐1650.0] | 1418.0 (320.3) [1070.0‐1920.0] |
| Portal flow rate (mL/minute/g) | 0.3 (0.1) [0.2‐0.4] | 0.5 (0.1) [0.4‐0.7] | 0.6 (0.1) [0.4‐0.7] | 0.6 (0.1) [0.4‐0.7] | 0.2 (0.1) [0.1‐0.4] | 0.6 (0.2) [0.4‐0.9] | 0.7 (0.1) [0.5‐0.9] | 0.7 (0.3) [0.5‐0.9] |
| Hematocrit, % | 29.0 (1.4) [27.8‐31.1] | 23.3 (5.4) [14.8‐29.5] | 16.0 (4.4) [11.3‐20.8] | 16.6 (6.0) [12.1‐23.4] | 26.2 (3.0) [20.8‐29.7] | 22.6 (1.3) [21.3‐24.0] | 21.3 (2.0) [18.9‐23.5] | 19.8 (2.3) [17.7‐23.0] |
| Oxygen consumption, mL/minute | 24.2 (1.4) [23.2‐25.2] | 34.1 (7.8) [25.1‐39.4] | 23.8 (13.7) [7.3‐39.6] | 46.8 (11.1) [31.0‐57.0] | 15.0 (13.3) [1.4‐37.0] | 34.2 (17.4) [15.8‐58.5] | 32.3 (15.7) [18.5‐83.9] | 54.2 (28.1) [18.5‐83.9] |
| Oxygen consumption, mass | 0.013 (0.002) [0.011‐0.014] | 0.017 (0.005) [0.013‐0.023] | 0.013 (0.006) [0.004‐0.017] | 0.027 (0.010) [0.018‐0.041] | 0.008 (0.008) [0.001‐0.021] | 0.018 (0.009) [0.008‐0.029] | 0.016 (0.008) [0.005‐0.024] | 0.027 (0.011) [0.011‐0.036] |
| Oxygen extraction ratio | 0.2 (0.1) [0.2‐0.3] | 0.2 (0.04) [0.2‐0.3] | 0.3 (0.3) [0.2‐0.8] | 0.3 (0.2) [0.2‐0.6] | 0.2 (0.1) [0.02‐0.3] | 0.2 (0.1) [0.1‐0.3] | 0.2 (0.1) [0.1‐0.2] | 0.3 (0.1) [0.1‐0.4] |
Data are given as mean (SD) [range].