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. 2019 Mar 6;3(7):e10182. doi: 10.1002/jbm4.10182

Figure 2.

Figure 2

Body and bone size, BMD, and bone strength parameters of ADH1 mice with or without treatment with PTH(1‐34) or calcilytic, JTT‐305. Parameter of bone strength of 19‐week‐old to 39‐week‐old WT littermates (white bars), ADH1 (gray bars), PTH(1‐34)‐treated ADH1 (black bars), and JTT‐305–treated ADH1 mice (diagonal bars). (A) Body weight (BW), (B) bone length of femur, (C) cortical area, (D) total BMD, (E) cortical BMD, (F) cancellous BMD, (G) breaking maximum load, (H) stiffness, (I) energy to breaking maximum load, (J) breaking maximum load/BW, (K) stiffness/bone length, (L) ultimate stress/total BMD, and (M) toughness/total BMD. Results are presented as means ± SD of 8 or more measurements. *p < 0.05, **p < 0.01, #p < 0.005, ##p < 0.001, compared with the group at the other end of bars.