Table 1.
Biochemical Evaluation of Patients 1 to 3, Pre‐RFA and Post‐RFA
| Patient 1 | Patient 2 | Patient 3 | |||||
|---|---|---|---|---|---|---|---|
| Parameters | Pre‐RFA | Post‐RFA (day 14) | Pre‐RFA | Post‐RFA (day 7) | Pre‐RFA | Post‐RFA (day 14) | Normal range |
| Albumin‐corrected total calcium (mg/dL) | 10.2, 10.3 | 9.3, 9.8 | 10.0, 9.7 | 9.4, 9.6 | 9.9, 9.5 | 9.5, 9.6 | 8.5–10.4 |
| Serum phosphorus (mg/dL) | 1.3, 1.5 | 2.8, 3.0 | 1.4, 1.5 | 3.1, 3.4 | 2.0, 1.8 | 3.1, 3.3 | 2.4‐4.4 |
| Serum ALP (U/L) | 279 | 286 | 705 | 221 | 212 | 272 | 30–120 |
| Serum 25(OH)D (ng/mL) | 19.3 | — | 62.6 | 54.2 | 49.6 | 52 | 50–250 |
| 1,25(OH)2D (pmol/L) | 20.0 | — | 38.2 | — | 50.1 | – | 47.7–190.3 |
| Intact PTH (pg/mL) | 52.7 | 81.6 | 52.7 | 61.0 | 212.0 | 41 | 14.0–72.0 |
| TRP (%) a | 81 | 90 | 80 | 91 | 75 | 90 | 88–95 |
| TMP/GFR (mg/dL) | 1.5 | 3.0 | 1.3 | 3.2 | 1.1 | 2.9 | 2.8–4.4 |
| c‐FGF‐23 (RU/mL) b | 453.0 | — | 960.0 | 135.0 | 101.8 | — | <180 |
| Site of lesion | Roof of right acetabulum | Left pectineus muscle | Angle and ramus of right mandible | — | |||
| Duration of follow‐up after RFA (months) | 24 | 24 | 10 | — | |||
RFA = radiofrequency ablation; ALP= alkaline phosphatase; 25(OH)D = 25 hydroxyvitamin D; 1,25(OH)2D = 1,25 dihydroxyvitamin D; PTH = parathyroid hormone; TRP = tubular reabsorption of phosphate; TMP/GFR = ratio of tubular maximum reabsorption of phosphate to glomerular filtration rate; c‐FGF‐23 = C‐terminal fibroblast growth factor‐23.
a
TRP (%) is calculated according to the formula: 100 × (1 − [urine phosphate/urine creatinine] × [serum creatinine/serum phosphate]).
b
Carboxy‐terminal FGF‐23 (ELISA, Immutopics, Inc., San Clemente, CA, USA).