. 2019 Jul 26;9:10867. doi: 10.1038/s41598-019-47074-y

Table 2.

Comparative antiviral activity of IFNα2b fusion proteins.

Fusion protein	EC₅₀ (pg/ml)	IU/ml	Specific activity (U/mg)	Percentage activity relative to IFNα2b
Latent IFNα2b-NS3-LAP	4000	2.1 × 10⁷	5.20 × 10⁵	0.2%
Pre-activated IFNα2b-NS3-LAP	22.22	1.3 × 10⁷	9.36 × 10⁷	36%
Real time activated IFNα2b-NS3-LAP	25	2.0 × 10⁷	8.32 × 10⁷	32%
Latent LAP-NS3-IFNα2b	5000	2.7 × 10⁷	4.16 × 10⁵	0.16%
Pre-activated LAP-NS3-IFNα2b	23.52	1.4 × 10⁷	8.84 × 10⁷	34%
Real time activated LAP-NS3-IFNα2b	26.66	1.3 × 10⁷	1.3 × 10⁷	30%
IFNα2b (standard)	8.0		2.6 × 10⁸	100%