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. 2019 Jul 26;10:3347. doi: 10.1038/s41467-019-11262-1

Fig. 2.

Fig. 2

Histological cross-section of a human macula. a Normal macula. b Hard drusen (*) within Bruch’s membrane. c A soft druse (*) within Bruch’s membrane. (b and c are courtesy of Philip Luthert, MBBS, UCL Institute of Ophthalmology.) d Subretinal drusenoid deposits (SDDs) between shortened photoreceptor outer segments and the RPE. Arrows highlight one of several SDDs (Courtesy of Christine Curcio, Ph.D., University of Alabama Birmingham and Project MACULA AMD Histopathology resource (http://projectmacula.cis.uab.edu/). HFL Henle fiber layer, NFL nerve fiber layer, GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer nuclear layer, POS photoreceptor outer segment, RPE retinal pigment epithelium, BM Bruch’s membrane. Bar = 25 μm