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. 2019 Jul 26;9:10858. doi: 10.1038/s41598-019-47402-2

Table 3.

Relationship between studied gene polymorphisms and neonatal anthropometric bioimpedance characteristics.

Factors Birth weight (kg) MUAC (cm) TST (cm)
Mean ± SD p+ Median[Q1; Q3] p+ Median[Q1; Q3] p+
BMI initial (kg/m 2 )
<25 3.33 ± 0.45 0.094 10.5[10.0; 11.3] 0.075 2.8[2.3; 3.4] 0.912
≥25 3.46 ± 0.45 11.0[10.5; 11.5] 2.9[2.4; 3.2]
GWG status
Insufficient 3.11 ± 0.49 <0.001 10.3[9.7; 10.8] 0.005 2.3[2.0; 2.8] <0.001
Normal 3.28 ± 0.43 10.5[10.2; 11.4] 2.8[2.4; 3.5]
Excessive 3.46 ± 0.42 11.0[10.5; 11.5] 2.3[2.0; 2.8]
MC4R rs17782313 Maternal SNP
TT 3.37 ± 0.43 0.892 11.0[10.3; 11.5] 0.149 2.9[2.3; 3.4] 0.519
CT + CC 3.36 ± 0.48 10.5[10.0; 11.5] 2.8[2.4; 3.5]
ENPP1 rs1044498 Maternal SNP
AA 3.35 ± 0.43 0.333 10.5[10.0; 11.3] 0.085 2.8[2.3; 3.2] 0.208
AC + CC 3.42 ± 0.49 11.0[10.3; 11.5] 3.0 [2.4; 3.4]
MC4R rs17782313 Neonates SNP
TT 3.40 ± 0.45 0.250 11.0[10.3; 11.5] 0.035 2.8[2.3; 3.2] 0.346
CT + CC 3.32 ± 0.48 10.5[10.0; 11.2] 3.0 [2.4; 3.4]
ENPP1 rs1044498 Neonates SNP
AA 3.35 ± 0.42 0.538 10.5[10.0; 11.4] 0.105 2.8[2.3; 3.2] 0.123
AC + CC 3.40 ± 0.45 11.0[10.3; 11.5] 3.0 [2.3; 3.5]

Legend: SD = standard deviation; Q1 = first quartile; Q3 = third quartile; +p-values obtained from Student-t test for independent samples, ANOVA test or nonparametric test (as Mann-Whitney or Kruskal-Wallis).

BMI: Body mass index, BW: birth weight, MUAC: Middle upper arm circumference, SD: standard deviation, TST: Tricipital skinfold thickness.

ENPP1 rs1044498 A > C: nucleotide pyrophosphatase/phosphodiesterase gene polymorphisms (AA = reference category); AA – homozygous for A allele; AC – heterozygous; CC - homozygous for C allele;

MC4R rs17782313 T > C: melanocortin- 4 receptor gene polymorphisms (TT = reference category); CC - homozygous for C allele; CT - heterozygous; TT- homozygous for T allele.