Table 3.
Factors | Birth weight (kg) | MUAC (cm) | TST (cm) | |||
---|---|---|---|---|---|---|
Mean ± SD | p+ | Median[Q1; Q3] | p+ | Median[Q1; Q3] | p+ | |
BMI initial (kg/m 2 ) | ||||||
<25 | 3.33 ± 0.45 | 0.094 | 10.5[10.0; 11.3] | 0.075 | 2.8[2.3; 3.4] | 0.912 |
≥25 | 3.46 ± 0.45 | 11.0[10.5; 11.5] | 2.9[2.4; 3.2] | |||
GWG status | ||||||
Insufficient | 3.11 ± 0.49 | <0.001 | 10.3[9.7; 10.8] | 0.005 | 2.3[2.0; 2.8] | <0.001 |
Normal | 3.28 ± 0.43 | 10.5[10.2; 11.4] | 2.8[2.4; 3.5] | |||
Excessive | 3.46 ± 0.42 | 11.0[10.5; 11.5] | 2.3[2.0; 2.8] | |||
MC4R rs17782313 Maternal SNP | ||||||
TT | 3.37 ± 0.43 | 0.892 | 11.0[10.3; 11.5] | 0.149 | 2.9[2.3; 3.4] | 0.519 |
CT + CC | 3.36 ± 0.48 | 10.5[10.0; 11.5] | 2.8[2.4; 3.5] | |||
ENPP1 rs1044498 Maternal SNP | ||||||
AA | 3.35 ± 0.43 | 0.333 | 10.5[10.0; 11.3] | 0.085 | 2.8[2.3; 3.2] | 0.208 |
AC + CC | 3.42 ± 0.49 | 11.0[10.3; 11.5] | 3.0 [2.4; 3.4] | |||
MC4R rs17782313 Neonates SNP | ||||||
TT | 3.40 ± 0.45 | 0.250 | 11.0[10.3; 11.5] | 0.035 | 2.8[2.3; 3.2] | 0.346 |
CT + CC | 3.32 ± 0.48 | 10.5[10.0; 11.2] | 3.0 [2.4; 3.4] | |||
ENPP1 rs1044498 Neonates SNP | ||||||
AA | 3.35 ± 0.42 | 0.538 | 10.5[10.0; 11.4] | 0.105 | 2.8[2.3; 3.2] | 0.123 |
AC + CC | 3.40 ± 0.45 | 11.0[10.3; 11.5] | 3.0 [2.3; 3.5] |
Legend: SD = standard deviation; Q1 = first quartile; Q3 = third quartile; +p-values obtained from Student-t test for independent samples, ANOVA test or nonparametric test (as Mann-Whitney or Kruskal-Wallis).
BMI: Body mass index, BW: birth weight, MUAC: Middle upper arm circumference, SD: standard deviation, TST: Tricipital skinfold thickness.
ENPP1 rs1044498 A > C: nucleotide pyrophosphatase/phosphodiesterase gene polymorphisms (AA = reference category); AA – homozygous for A allele; AC – heterozygous; CC - homozygous for C allele;
MC4R rs17782313 T > C: melanocortin- 4 receptor gene polymorphisms (TT = reference category); CC - homozygous for C allele; CT - heterozygous; TT- homozygous for T allele.