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. Author manuscript; available in PMC: 2019 Jul 26.
Published in final edited form as: Oral Oncol. 2018 Jun 30;84:12–19. doi: 10.1016/j.oraloncology.2018.06.022

Table 4.

Toxicity Incidence.

All Patients nD DnM D + M p
(D + M v nD)
p
(D + M v DnM)

N % n % n % n %
All Patients 1646 100.0 1144 100.0 378 100.0 124 100.0 . .
Weight Loss No 1078 65.5 764 66.8 233 61.6 81 65.3 0.74 0.46
Yes 568 34.5 380 33.2 145 38.4 43 34.7 . .
Antiemetic Prescription No 875 53.2 603 52.7 209 55.3 63 50.8 0.69 0.38
Yes 771 46.8 541 47.3 169 44.7 61 49.2 . .
ED Visit No 1161 70.5 818 71.5 262 69.3 81 65.3 0.15 0.41
Yes 485 29.5 326 28.5 116 30.7 43 34.7 . .
Hospital/ED Visit w/Nausea/Emesis No 1360 82.6 944 82.5 312 82.5 104 83.9 0.71 0.73
Yes 286 17.4 200 17.5 66 17.5 20 16.1 . .
Hospital/ED Visit w/Dehydration No 1201 73.0 834 72.9 277 73.3 90 72.6 0.94 0.88
Yes 445 27.0 310 27.1 101 26.7 34 27.4 . .
Hospital/ED Visit w/Malnutrition No 1225 74.4 857 74.9 275 72.8 93 75.0 0.98 0.62
Yes 421 25.6 287 25.1 103 27.3 31 25.0 . .
Gastrostomy or Feeding Tube No 1015 61.7 718 62.8 224 59.3 73 58.9 0.40 0.94
Yes 631 38.3 426 37.2 154 40.7 51 41.1 . .
Dysphagia No 866 52.6 618 54.0 187 49.5 61 49.2 0.31 0.96
Yes 780 47.4 526 46.0 191 50.5 63 50.8 . .
Tracheostomy or Airway Obstruction No 1225 74.4 852 74.5 274 72.5 99 79.8 0.19 0.10
Yes 421 25.6 292 25.5 104 27.5 25 20.2 . .
Speech Pathology No 1343 81.6 937 81.9 305 80.7 101 81.5 0.90 0.85
Yes 303 18.4 207 18.1 73 19.3 23 18.6 . .

Abbreviations: ED, emergency department; nD, non-diabetic; DnM, diabetic not taking metformin; D + M diabetic taking metformin.