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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Pflugers Arch. 2018 Nov 13;471(3):441–453. doi: 10.1007/s00424-018-2227-8

Fig. 3.

Fig. 3

Endurance exercise training, performed prior to treatment with DOX, protects rodent skeletal muscle fibers against DOX-induced (A) oxidative stress (protein carbonyls), (B) calpain activation, and (C) degradation of the contractile protein actin. Data are from Smuder et al. [94]. Key: SED = sedentary controls; EXTR = endurance exercise trained; SEDDOX= sedentary animals treated with DOX; EXTRDOX= endurance exercise trained and treated with DOX; * = different (P<0.05) from all other groups.