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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Pflugers Arch. 2018 Nov 13;471(3):441–453. doi: 10.1007/s00424-018-2227-8

Fig. 5.

Fig. 5

Treatment of animals with a mitochondrial-targeted peptide (SS-31) prevents MV-induced increases in mitochondria emission of reactive oxygen species (H2O2) during both (A) state 3 and (B) state 4 respiration and also protects against (C) MV-induced atrophy of diaphragm muscle fibers. Data are from Powers et al. [75]. Key: CON = animals with no experimental treatment; MV = animals exposed to 12 hours of mechanical ventilation; MV-SS31 = animals exposed to 12 hours of mechanical ventilation and treated with the mitochondrial-targeted peptide SS-31; * = different (P<0.05) from all other groups.