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. 2019 Jul 22;12:331–336. doi: 10.2147/CEG.S214196

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© 2019 Tsugawa et al.

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Impaired hepatocyte proliferation after liver resection in the ERα knockout (KO) mice. Wild-type (WT) and KO mice underwent partial hepatectomy (PH), and the rate of hepatocyte proliferation was assessed for up to 72 h after PH. (A) Bromodeoxyuridine (BrdU) was injected 2 h before dissection. BrdU-positive hepatocytes were counted by immunocytochemistry. (B) Mitotic bodies were counted in liver sections. Values are expressed as the mean ± SEM (n=5–17 per group); *p<0.05.