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. 2019 Jul 22;12:331–336. doi: 10.2147/CEG.S214196

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© 2019 Tsugawa et al.

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The ERα is involved in the lipid metabolism after liver resection. (A) Wild-type (WT) and knockout (KO) male mice were operated with partial hepatectomy (PH) or sham operation, and their livers were analyzed by hematoxylin and eosin or Oil Red O staining. (B) Reduced transcripts of ACS (acyl-coA synthetase), AOX (acyl-coA oxidase) and their regulator PPARα were observed in ERα KO male mice after PH, suggesting that ERα regulates β-oxidation enzyme gene expression.