Table 3.

Relationship between SHP2 and Hook1 expression and clinical characteristics

Characteristic	Number	Hook1		x2	p	SHP2		x2	p
–	+	–	+
Median age
<60	50	23	27	0.008	0.927	25	25	2.887	0.089
≥60	51	23	28			17	34
Sex
Female	27	11	16	0.343	0.558	15	12	2.961	0.085
Male	74	35	39			27	47
Smoking status
yes	61	29	32	0.248	0.619	21	40	3.249	0.071
no	40	17	23			21	19
Performance status
0	76	34	42	0.203	0.652	33	43	0.263	0.608
1 and 2	24	12	12			9	15
Histology
Squamous	27	17	10	5.629	0.06	12	15	0.633	0.729
Adenocarcinoma	56	20	36			24	32
others	18	9	9			6	12
UICC Stage
I–IIIa	71	38	33	4.417	0.036*	31	40	0.5	0.479
IIIb–IV	30	9	21			11	19

Note: *P<0.05 was considered statistically significant.