Table 5.
Univariate/Multivariate Cox-regression analysis for overall survival in NSCLC patients
| Factors | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95.0% CI | p | HR | 95.0% CI | p | |
| Sex (males VS females) | 1.010 | 0.611–1.669 | 0.970 | |||
| Age, yr (<60 VS ≥60) | 0.879 | 0.561–1.377 | 0.574 | |||
| Smoking status (Yes VS No.) | 0.863 | 0.546–1.363 | 0.527 | |||
| Histology (Squamous VS Adenocarcinoma VS others) | 1.562 | 1.097–2.223 | 0.013* | 1.462 | 1.034–2.096 | 0.039* |
| Performance status (0 VS.1 or 2) | 1.182 | 0.695–2.010 | 0.538 | |||
| Pathologic stage (Stage I-IIIa vs stage IV) | 1.597 | 0.999–2.553 | 0.050* | 1.273 | 0.779–2.080 | 0.336 |
| Hook1 (High VS low) | 1.168 | 0.928–1.470 | 0.187 | |||
| SHP2 (High VS low) | 1.412 | 1.107–1.803 | 0.006* | 1.400 | 1.093–1.792 | 0.008* |
Note: *P<0.05 was considered statistically significant.
Abbreviations: HR, hazard ratio; CI confidence interval.