Table 1.
Demographic of subjects with and without LTBI (n=6,083)
| N (%) of LTBI (positive TST or QFT), n=658 | N (%) of non-LTBI, n=5,425 | P-value | |
|---|---|---|---|
| Age, year | <0.0001 | ||
| 6–14 | 24 (2.15) | 1,249 (11.91) | |
| 15–24 | 53 (8.45) | 931 (14.62) | |
| 25–44 | 162 (29.59) | 1,270 (28.36) | |
| 45–64 | 267 (40.60) | 1,214 (30.48) | |
| ≥65 | 152 (19.21) | 761 (14.64) | |
| Male | 375 (54.77) | 2,660 (47.78) | 0.0036 |
| Race/ethnicity | <0.0001 | ||
| Nonhispanic white | 80 (30.93) | 1,947 (68.10) | |
| Nonhispanic black | 154 (14.73) | 1,517 (11.78) | |
| Mexican american | 107 (19.31) | 706 (8.39) | |
| Asian | 184 (16.84) | 529 (3.18) | |
| Other | 133 (18.19) | 726 (8.54) | |
| Birthplace | <0.0001 | ||
| US | 221 (44.87) | 4,423 (88.72) | |
| Foreign | 437 (55.13) | 1,000 (11.28) | |
| Ever lived with someone with active TB | 41 (7.39) | 135 (2.19) | <0.0001 |
| Education | 0.0002 | ||
| < high school graduate | 268 (35.81) | 2,427 (29.19) | |
| High school graduate/GED or more | 135 (23.38) | 840 (17.29) | |
| Beyond high school | 255 (40.81) | 2,155 (53.5%) | |
| Poverty income ratio | <0.0001 | ||
| ≥1 (nonpoverty) | 411 (73.23) | 3,609 (81.76) | |
| <1 (poverty) | 174 (26.77) | 1,434 (18.24) | |
| Smoking status | 0.4318 | ||
| Nonsmoker | 367 (56.87) | 2,993 (58.63) | |
| Passive smoker | 152 (19.48) | 1,478 (19.67) | |
| Active smoker | 139 (23.64) | 954 (20.21) | |
| Underlying disease | |||
| Diabetes | 99 (13.34) | 443 (7.57) | 0.0031 |
| HIV status | 2 (0.41) | 14 (0.39) | 0.9468 |
| Malignancy | 37 (7.25) | 311 (9.71) | 0.3018 |
| Hypertension | 233 (34.60) | 1,335 (30.55) | 0.1285 |
| Hypercholesterolemia | 246 (38.76) | 1,184 (33.96) | 0.0263 |
| eGFR | 0.1543 | ||
| eGFR <60 | 49 (6.58) | 351 (8.03) | |
| eGFR 60–90 | 240 (38.79) | 1,495 (41.87) | |
| eGFR >90 | 340 (54.63) | 2,614 (50.10) | |
| Previous TST testing | |||
| Previous positive TST | 117 (29.30) | 101 (3.18) | <0.0001 |
| Previous IGRA testing | |||
| History of TB disease | 23 (3.22) | 9 (0.08) | <0.0001 |
| Ever alcohol use | 362 (71.92) | 2,599 (80.52) | 0.0015 |
| Season | 0.0108 | ||
| Winter (Nov-April) | 329 (55.37) | 2,649 (45.57%) | |
| Summer (May-Oct) | 329 (44.63) | 2,776 (54.43 | |
| 25(OH)D ng/mla | 25.08 (23.63–26.52) | 28.14 (26.74–29.55) | 0.0012 |
| Vit D categories | <0.0001 | ||
| ≥30 | 165 (27.25) | 1,513 (39.74) | |
| 20–29 | 232 (37.07) | 2,047 (36.53) | |
| 12–19 | 189 (26.50) | 1,396 (18.78) | |
| <12 | 64 (9.18) | 416 (4.96) |
Notes: aValues are weighted means (95% CI).
Abbreviations: eGFR, estimated glomerular filtration rate; TST, tuberculin skin test; IGRA, interferon-gamma release assay; LTBI, latent tuberculosis infection.