Methods |
Randomised, double‐blind, placebo‐controlled study. |
Participants |
67 pregnant women with vitamin D (25(OH)D) level lower than 25 ng/mL, English or Spanish literacy, age 18 years and gestational age less than 20 weeks. |
Interventions |
Women were randomised to: group 1 (n = 36) received 50,000 IU vitamin D3 or group 2 (n = 31) received placebo, once a week for 8 weeks in addition to a prenatal vitamin with 400 IU vitamin D3. |
Outcomes |
After 8 weeks of treatment, VD levels were 48.1 19.6 ng/mL and 21.1 5.9 ng/mL (P <.0001) with 84.4% and 3.9% achieving VD sufficiency (> 30 ng/mL) in the TG and PG, respectively (P <.0001). At delivery, VD levels were 28.8 9.8 ng/mL and 20.58.9 ng/mL in the TG and PG, respectively (P < 0.0027). |
Notes |
Mount Sinai, West Hospital, New York, NY, USA |